The result of this research shows the economic and clinical benefits of the
use of different pharmacological treatments for adult kidney transplant
recipients in Colombia, considering the years of life gained and organ
rejection avoided. Tacrolimus and cyclosporine are the most used options in
clinical practice for maintenance therapy and are included in the cost-
effective schemes.
Across the different sets of evidence, tacrolimus+mycophenolate
mofetil+corticosteroids, cyclosporine + mycophenolate
mofetil+corticosteroids, and cyclosporine+ azathioprine+corticosteroids
proved to be the cost-effective strategies in most comparisons.

Social preference values of health states are a fundamental input for the preparation of studies in health economics. Several countries have undertaken studies to obtain these values. Our objective was to conduct a structured and systematic literature review of articles that calculates this set of representative values at the national level in low- and middle-income countries (LMICs).

Tacrolimus and cyclosporine are the most used options in clinical practice for maintenance therapy. In this study, we performed a cost-effectiveness analysis of tacrolimus versus cyclosporine, evaluating the cost-effective therapeutic scheme in the Colombian context, considering organ rejection avoided as a clinical outcome. The result of this research shows the economic and clinical benefits of the use of both therapeutic schemes, tacrolimus only achieves cost-effectiveness in 1 treatment regimen, being above the cost-effectiveness threshold in the remaining regimen.